INSIGHTS ON GENOMIC AND MOLECULAR ALTERATIONS IN MULTIPLE MYELOMA AND THEIR INCORPORATION TOWARDS RISK-ADAPTED TREATMENT STRATEGY: CONCISE CLINICAL REVIEW

Insights on Genomic and Molecular Alterations in Multiple Myeloma and Their Incorporation towards Risk-Adapted Treatment Strategy: Concise Clinical Review

Although recent advances in novel treatment approaches and therapeutics have shifted the treatment landscape of multiple myeloma, it remains an incurable plasma cell malignancy.Growing knowledge of the genome and expressed genomic information characterizing the Toddler Bottoms biologic behavior of multiple myeloma continues to accumulate.However, t

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A retractable barb needle for drug darts

The mechanism and action of a new retractable barbneedle for drug darts are described.This dart needle is particularly successful in obviating unnecessary flight reactions andtrauma in darted animals, and Climbing Set facilitates the complete injection of the drug dose before the barb is retracted and the dart is dislogded from the animal.The whole

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Mouse Models of Liver Parenchyma Injuries and Regeneration

Mice have genetic and physiological similarities with humans and a well-characterized genetic background that is easy to manipulate.Murine models have become the most favored, robust mammalian systems for experimental analyses of biological processes and disease conditions due to their low cost, rapid reproduction, a wealth of mouse strains with de

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Reduced graphene oxide coating enhances osteogenic differentiation of human mesenchymal stem cells on Ti surfaces

Abstract Background Titanium (Ti) has been utilized as hard tissue replacement owing to its superior mechanical and bioinert property, however, Wheel Spacer lack in tissue compatibility and biofunctionality has limited its clinical use.Reduced graphene oxide (rGO) is one of the graphene derivatives that possess extraordinary biofunctionality and ar

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